cover image THE TRUTH ABOUT THE DRUG COMPANIES: How They Deceive Us and What to Do About It

THE TRUTH ABOUT THE DRUG COMPANIES: How They Deceive Us and What to Do About It

Marcia Angell. Random, $24.95 (336pp) ISBN 978-0-375-50846-2

In what should serve as the Fast Food Nation of the drug industry, Angell, former editor of the prestigious New England Journal of Medicine, presents a searing indictment of "big pharma" as corrupt and corrupting: of Congress, through huge campaign contributions; of the FDA, which is funded in part by the very companies it oversees; and, perhaps most shocking, of members of the medical profession and its institutions. Angell delineates how the drug giants, such as Pfizer and AstraZeneca, pay physicians to prescribe their products with gifts, junkets and marketing programs disguised as "professional education." According to Angell, the cost of marketing, both to physicians and consumers, far outweighs expenditures on research and development, though drug makers invoke R&D as the reason drug prices are so high. In fact, says Angell, with combined 2002 profits of $35.9 billion for the Fortune 500's top 10 drug companies, the drug industry is America's most profitable by far, thanks to disproportionately high prices, generous tax breaks and manipulation of patents to extend exclusive marketing rights to blockbuster drugs like Prozac and Claritin. Angell mounts a powerful case (and offers specific suggestions) for reform of this essential industry—a case worth bearing in mind as "big pharma" continues to oppose importing cheaper drugs from Canada. Agent, Martel Agency. (On sale Aug. 24)

Forecast: Time called Angell one of the 25 most influential Americans, and with the high cost of drugs making front-page news, her book should find a receptive audience.