cover image THE MOLD IN DR. FLOREY'S COAT: The Story of Penicillin and the Modern Age of Medical Miracles

THE MOLD IN DR. FLOREY'S COAT: The Story of Penicillin and the Modern Age of Medical Miracles

Eric Lax, . . Holt, $25 (307pp) ISBN 978-0-8050-6790-3

This book sets out to correct the misapprehension that Alexander Fleming, the first scientist to discover the antibacterial properties of the mold Penicillium notatum , was also responsible for developing the wonder drug that saved countless lives and ushered in the era of modern medicine. Although Fleming coined the term "penicillin," his tentative research on the mold produced few valuable results and was prematurely abandoned. More than a decade later, in 1940, a pathology team at Oxford University—headed by Howard Florey, Ernst Chain and the now almost forgotten Norman Heatley—resumed Fleming's preliminary work and eventually developed the world's first viable antibiotic. Although Fleming, Florey and Chain shared a Nobel Prize in 1945 for their revolutionary work, accolades and media attention were disproportionately bestowed on Fleming, and in the popular imagination he was transformed into the sole creator of penicillin. Lax (Woody Allen ; Life and Death on 10 West ) has written a commendable account of this historical oversight, conveying the thrill of discovery during the upheaval of WWII and skillfully translating the abstruse technicalities of lab work and medical jargon into enjoyable prose. Yet this book also shows that monumental discoveries are not always born of monumental stories, and the narrative contains trivial details and petty grievances that made up these scientists' circumscribed lives. Lax's treatment is disciplined and focused, but it would have been improved by a broader historical sweep and more involved discussions of penicillin's impact on the pharmaceutical industry. 18-page b&w photo insert not seen by PW . (Apr.)