Sacred Cows and Golden Geese

In this compelling report, anesthesiologist Ray Greek and veterinarian Jean Swingle Greek argue against the use of animals in medical experiments. Although the Greeks believe that animal experiments are immoral and wasteful, they avoid the philosophical arguments used by most animal rights activists to generate sympathy for animals. Instead, they marshal a devastating amount of scientific evidence about the human consequences of animal-based medical research. Because of important differences in animal and human physiology, they contend, animals often have a wildly different response to diseases and medications than do humans--according to the authors, every year roughly 100,000 Americans die of adverse reactions to drugs that proved, in animals, to be perfectly safe. Why then do we continue to support widespread animal testing? They pack their well-written, shocking expos with horror stories--about the unnecessary expense of animal experiments; about medications that, though animal tests suggested they were safe, caused liver and heart failure, hemorrhages and death in humans; and about the potentially life-saving drugs that have been kept off the market for humans because they cause harmful side effects in animals. Throughout, the authors make a strong case for the adoption of nonanimal research alternatives such as clinical observation, in vitro and epidemiological studies, diagnostic imaging of patients, mandatory postmarketing drug surveillance, autopsies, computer modeling and larger, longer clinical trials. Their powerful, courageous appeal is essential reading for concerned citizens and open-minded physicians, veterinarians and scientists. (May)