The Lust Lizard of Melancholy Cove

With in-your-face, South Park-worthy humor that only once slips into the truly offensive, Moore (Island of the Sequined Love Nun) has written the definitive Prozac allegory. Like its Puff-the-Libidinous-Dragon protagonist Steve, this novel delightfully runs roughshod over trailer parks, scrip-happy psychiatrists, right-wing moralists and ""nuked-out future movie"" stars with laugh-aloud wit and gentle affection. Pine Cove is a Pacific coast town of 5000--a third of whom Dr. Valerie Riordan has rendered dependent on antidepressants. When obsessive-compulsive Bess Leander is found hanged from a calico cloth rope, a possible suicide, Val fears she has been overmedicating, and she blackmails fish-fetishist pharmacist Winston Krauss into giving all antidepressant users placebos instead. As the antidepressants wear off, a hilariously uncontrollable erotic revolution takes place in the formerly groggy and dispirited population. A simultaneous nuclear plant leak into the ocean awakens serotonin-deficit sea beast Steve, who descends on the town, disguised occasionally as a double-wide mobile home. When the doper constable and the methamphetamine-peddling sheriff duke it out, creating chaos instead of restoring order, we learn our lesson about better living through pharmaceuticals. Moore is Daniel Pinkwater for grownups, but a lot funnier; and his irreverent antics reveal a buoyant wit and surreal authority even while rendering the emotional range, sex life, and murderous tendencies of a sea monster. Agent: Nick Ellison. Author tour. (Mar.)