John Green will publish his second book of nonfiction, Everything Is Tuberculosis: The History and Persistence of Our Deadliest Infection, next year as the first title from a new imprint at Penguin Young Readers, Crash Course Books. The deal, brokered by Jodi Reamer of Writers House, will see the book published in both hardcover and e-book formats on March 18, with an announced first print run of 500,000 copies; it will also be adapted to audiobook format by Listening Library, with Green set to narrate.

The imprint, per the release, is an “extension” of the bestselling author’s hit YouTube channel of the same name, run with his brother, Hank, and is “devoted to publishing nonfiction for students and lifelong learners.” Dutton Children's Books president and publisher Julie Strauss-Gabel heads up the new shingle; two new series, Crash Course Revolutions and Crash Course Lit, will follow in fall 2025.

Everything Is Tuberculosis, the publisher said, “traces the journey of a young tuberculosis patient in Sierra Leonne woven together with the scientific and social histories of how this disease has shaped our world and how our choices will shape the future of tuberculosis. This book builds on Green’s nationally recognized advocacy for increased awareness of the healthcare inequities that allow this curable, treatable infectious disease to also be the deadliest, killing 1.5 million people every year.”

“This book is the culmination of a long journey toward trying to understand how a disease that has been curable since the 1950s continues to kill over a million people every year,” Green said in a statement. I’m thrilled to be publishing it as the first title from Crash Course Books, and so grateful to all the TB researchers and survivors whose generosity with me made it possible for me to tell this story.”

This article has been updated for clarity.