A rich fall season gets even more tempting, as Michael Crichton probes some unexpected twists in gene therapy and Thomas Pynchon looks back at turn-of-the-century New York, Europe and Central Asia. In children's books, Eloise is back in the spotlight.

NOVEMBER 1* The 12 Days of Christmas (Anniversary Edition) by Robert Sabuda (Little Simon, $26.95). 275,000 copies.Redneck Woman: Stories from My Life by Gretchen Wilson with Allen Rucker (Warner, $23.99). 200,000 copies.* Kay Thompson's Eloise in Hollywood, based on the art of Hilary Knight, written by J. David Stem and David Weiss, illus. by Ted Enik (Simon & Schuster, $17.95). 150,000 copies.NOVEMBER 2
The Varieties of Scientific Experience: A Personal View of the Search for God by Carl Sagan, edited by Ann Druyan (Penguin Press, $27.95) 150,000 copies.
NOVEMBER 6
* Wild Fire by Nelson DeMille (Warner, $26.99). 1 million copies.
NOVEMBER 7
* Inés of My Soul by Isabel Allende (HarperCollins, $25.95). 250,000 copies.
The House of Hilton: From Conrad to Paris—A Drama of Wealth, Power, and Privilege by Jerry Oppenheimer (Crown, $24.95). 100,000 copies.
The Doors by the Doors (Hyperion, $45). 100,000 copies.
Point to Point Navigation: A Memoir by Gore Vidal (Doubleday, $26). 75,000 copies.
A Christmas Secret by Anne Perry (Ballantine, $16.95).
* The Rising Tide: A Novel of the Second World War by Jeff Shaara (Ballantine, $27.95).
The Gods of Newport by John Jakes (Dutton, $26.95).
Born in Death by Nora Roberts writing as J.D. Robb (Putnam, $24.95).
Since Then: How I Survived Everything and Lived to Tell About It by David Crosby with Carl Gottlieb (Putnam, $26.95).
The Godfather's Revenge by Mark Winegardner (Putnam, $25.95).
The Shepherd, the Angel, and Walter the Christmas Miracle Dog by Dave Barry (Putnam, $15.95).
The Handmaid and the Carpenter by Elizabeth Berg (Random, $17.95).
NOVEMBER 13
Cross by James Patterson (Little, Brown, $27.99). 1.5 million copies.
NOVEMBER 14
Santa Cruise by Mary Higgins Clark and Carol Higgins Clark (Scribner, $22). 550,000 copies.
* The Dragon's Eye: The Dragonology Chronicles, Volume 1 by Dugald A. Steer, illus. by Douglas Carrel (Candlewick, $15.99). 225,000 copies.
Empire by Orson Scott Card (Tor, $24.95). 175,000 copies.
Home: The Blueprint of Our Lives, edited by John Edwards (Collins, $29.95). 150,000 copies.
The Long Night of Winchell Dear by Robert James Waller (Shaye Areheart, $21). 150,000 copies.
NOVEMBER 21
* The Shape Shifter by Tony Hillerman (HarperCollins, $26.95). 500,000 copies.
Against the Day by Thomas Pynchon (Penguin Press, $35).
John's Story: The Last Eyewitness (The Jesus Chronicles) by Tim LaHaye and Jerry Jenkins (Putnam, $24.95).
NOVEMBER 28
Next by Michael Crichton (HarperCollins, $27.95). 2 million copies.
Brother Odd by Dean Koontz (Bantam, $27). 650,000 copies.
Temperatures Rising by Sandra Brown (Bantam, $20). 100,000 copies.
Treasure of Khan by Clive Cussler and Dirk Cussler (Putnam, $27.95).

—with reporting by Raya Kuzyk

* = Children's titles

* = PW starred review

For a complete list of major titles going on sale between now and April 2007, visit www.publishersweekly.com